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Cadherin-19 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70595Amount:
100ulMolecular Weight:
88073DaApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human CDH18. AA range:101-150Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using Cadherin-18 Polyclonal Antibody
Gene Name:
CDH18Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
Cadherin-18Human Gene Id:
1016Human Swiss Prot No:
Q13634Specificity:
Cadherin-18 Polyclonal Antibody detects endogenous levels of Cadherin-18 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CDH18; CDH14; Cadherin-18; Cadherin-14Observed Band(KD):
88Background:
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],Function:
function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,Subcellular Location:
Cell membrane; Single-pass type I membrane protein.Expression:
Brain,Cerebellum,
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