Product Information
Molecular Weight36434DaObserved Band:38KD
Protein NameCarbonic anhydrase 5B mitochondrial
Human Gene Id11238
Human Swiss Prot NoQ9Y2D0
Mouse Gene Id56078
Mouse Swiss Prot NoQ9QZA0
Rat Gene Id302669
Rat Swiss Prot NoQ66HG6
SpecificityCA VB Polyclonal Antibody detects endogenous levels of CA VB protein
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCA5B; Carbonic anhydrase 5B; mitochondrial; Carbonate dehydratase VB; Carbonic anhydrase VB; CA-VB
Functioncatalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide.,similarity:Belongs to the alpha-carbonic anhydrase family.,tissue specificity:Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver.,
Subcellular Locationmitochondrion,mitochondrial matrix,
ExpressionBlood,Pancreas,,
Backgroundcarbonic anhydrase 5B(CA5B) Homo sapiens Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008],