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C/EBP ε Polyclonal Antibody
Datasheet
Catalog Number:
E20-70558Amount:
100ulMolecular Weight:
30603DaApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human C/EBP-epsilon. AA range:40-89Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of Jurkat cells using C/EBP ε Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Gene Name:
CEBPEDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.Protein Name:
CCAAT/enhancer-binding protein epsilonHuman Gene Id:
1053Human Swiss Prot No:
Q15744Mouse Swiss Prot No:
Q6PZD9Specificity:
C/EBP ε Polyclonal Antibody detects endogenous levels of C/EBP ε protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CEBPE; CCAAT/enhancer-binding protein epsilon; C/EBP epsilonObserved Band(KD):
34Background:
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],Function:
function:C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.,online information:CEBPE mutation db,PTM:Phosphorylated.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP delta.,tissue specificity:Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.,Subcellular Location:
Nucleus .Expression:
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.
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