Product Information
Molecular Weight28467/30603 Da
Protein NameCCAAT/enhancer-binding protein delta/epsilon
Human Gene Id1052/1053
Human Swiss Prot NoP49716/Q15744
Mouse Gene Id12609/110794
Rat Gene Id25695/25410
Rat Swiss Prot NoQ03484/P56261
SpecificityC/EBP δ/ε Polyclonal Antibody detects endogenous levels of C/EBP δ/ε protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCEBPD; CCAAT/enhancer-binding protein delta; C/EBP delta; Nuclear factor NF-IL6-beta; NF-IL6-beta; CEBPE; CCAAT/enhancer-binding protein epsilon; C/EBP epsilon
Observed Band(KD)28
Functionfunction:C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1.,
Subcellular Locationnucleus,
ExpressionCerebellum,Placenta,
BackgroundCCAAT/enhancer binding protein delta(CEBPD) Homo sapiens The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010],