Product Information
Molecular Weight66203Da
Protein NameZinc finger MYND domain-containing protein 11
Human Gene Id10771
Human Swiss Prot NoQ15326
Mouse Swiss Prot NoQ8R5C8
SpecificityBS69 Polyclonal Antibody detects endogenous levels of BS69 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameZMYND11; BS69; Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; Protein BS69
Functionfunction:Binds to the transactivation domain of the adenovirus type 5 E1A 32 kDa protein (289R) and inhibits its transactivating activity. May act as tumor suppressor through suppression of adenovirus replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,
Subcellular Locationnucleus,nucleoplasm,chromosome,integral component of membrane,
ExpressionBrain,Colon carcinoma,Pancreas,Peripheral Nervous System,
Backgroundzinc finger MYND-type containing 11(ZMYND11) Homo sapiens The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],