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Brn-3a Polyclonal Antibody
Datasheet
Catalog Number:
E20-70529Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human POU4F1. AA range:311-360Source:
Polyclonal, RabbitGene Name:
POU4F1Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
- Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
Background:
POU class 4 homeobox 1(POU4F1) Homo sapiens This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012],Protein Name:
POU domain class 4 transcription factor 1Human Gene Id:
5457Human Swiss Prot No:
Q01851Mouse Gene Id:
18996Mouse Swiss Prot No:
P17208Rat Swiss Prot No:
P20266Specificity:
Brn-3a Polyclonal Antibody detects endogenous levels of Brn-3a protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
POU4F1; BRN3A; RDC1; POU domain; class 4, transcription factor 1; Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1MolecularWeight(Da):
42940Observed Band(KD):
42Function:
developmental stage:Expression peaks early in embryogenesis (day 13.5) and is undetectable 14 days after birth.,function:Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.,similarity:Belongs to the POU transcription factor family. Class-4 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,tissue specificity:Brain. Seems to be specific to the retina. Present in the developing brain, spinal cord and eye.,Subcellular Location:
nuclear chromatinExpression:
B-cell,Colon,Skin,
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Catalog Number
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