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BMP-8B Polyclonal Antibody
Datasheet
Catalog Number:
E20-70506Amount:
100ulMolecular Weight:
44768DaObserved Band:45KDApplications:
WB;ELISAReactivity:
Human;Rat;Mouse;Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human BMP8B. AA range:261-310Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using BMP-8B Polyclonal Antibody diluted at 1:2000
Gene Name:
BMP8BDilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Bone morphogenetic protein 8BHuman Gene Id:
656Human Swiss Prot No:
P34820Mouse Swiss Prot No:
P55105Specificity:
BMP-8B Polyclonal Antibody detects endogenous levels of BMP-8B protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
BMP8B; BMP8; Bone morphogenetic protein 8B; BMP-8; BMP-8B; Osteogenic protein 2; OP-2Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],Function:
function:Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.,online information:Bone morphogenetic protein 8b entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,Subcellular Location:
Secreted .Expression:
Hippocampus,Testis,
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