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BMP-8A Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70505

  • Amount:

    100ul

  • Molecular Weight:

    44798DaObserved Band:45KD

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human BMP8A. AA range:253-302

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using BMP-8A Polyclonal Antibody

  • Gene Name:

    BMP8A

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Bone morphogenetic protein 8A

  • Human Gene Id:

    353500

  • Human Swiss Prot No:

    Q7Z5Y6

  • Mouse Swiss Prot No:

    P34821

  • Specificity:

    BMP-8A Polyclonal Antibody detects endogenous levels of BMP-8A protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    BMP8A; Bone morphogenetic protein 8A; BMP-8A

  • Background:

    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],

  • Function:

    function:Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.,online information:Bone morphogenetic protein 8A entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,

  • Subcellular Location:

    Secreted .

  • Expression:

    Brain,Hippocampus,Thyroid gland,

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Catalog Number

  • Amount:100ul
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