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Bcl-2 Antibody
Datasheet   

  • Catalog Number:

    E20-70471

  • Amount:

    1mg/ml

  • Molecular Weight:

    (26266Observed Band(KD)：26

  • Price:

    225$

  • Applications:

    WB, IHC-p, IF, ELISA

  • Reactivity:

    HumanHuman Gene Id：596Human Swiss Prot No：P10415Mouse Swiss Prot No：P10417

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human BCL-2. AA range:26-75

  • Specificity/Sensitivity:

    Bcl-2 Polyclonal Antibody detects endogenous levels of Bcl-2 protein.

  • Storage/Stability:

    Stability：-20°C/1 yearOther Name：BCL2; Apoptosis regulator Bcl-2

  • Source:

    Rabbit

  • Western blot analysis of lysates from MCF7 cells, treated with Etoposide, using BCL-2 Antibody. The lane on the right is blocked with the synthesized peptide.

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

  • Background:

    BCL2, apoptosis regulator(BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.Function：A chromosomal aberration involving BCL2 may be a cause of follicular lymphoma (FL) [MIM:151430]; also known as type II chronic lymphatic leukemia.

  • Cellular localization:

    nucleus, cytoplasm, mitochondrion, mitochondrial outer membrane, endoplasmic reticulum,endoplasmic reticulum membrane, cytosol,membrane, integral component of membrane, nuclear membrane, mitochondrial membrane, myelin sheath.Expression： Testis

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BCL-2 Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:1mg/ml
  • Price:225$

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