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Cell Signal Transduction Research Antibodies
B-ATF Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight14120 Da
Protein NameBasic leucine zipper transcriptional factor ATF-like
Human Gene Id10538
Human Swiss Prot NoQ16520
Mouse Gene Id53314
Mouse Swiss Prot NoO35284
SpecificityB-ATF Polyclonal Antibody detects endogenous levels of B-ATF protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameBATF; Basic leucine zipper transcriptional factor ATF-like; B-cell-activating transcription factor; B-ATF; SF-HT-activated gene 2 protein; SFA-2
Functionfunction:Functions as a negative regulator of AP-1 mediated transcription by binding to Jun proteins. Jun/B-ATF heterodimers bind DNA preferentially at the 12-O-tetradecanoylphorbol-13-acetate response element (TRE) (consensus: 5'-TGA[CG]TCA-3') and weaker at the cAMP-responsive region (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), but are transcriptionally inert.,PTM:Phosphorylated.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Forms heterodimers with JUN, JUNB and JUND. Also interacts with IFI35.,tissue specificity:Expressed at highest levels in lung, and at lower levels in placenta, liver, kidney, spleen, and peripheral blood. Detected in SW480 colorectal cancer cell line and several hematopoietic tumor cell lines, including Raji Burkitt's lymphoma. Strongly expressed in mature B- and T-lymphocytes. According to PubMed:10777209 also expressed in moderate
Subcellular Locationnucleus,cytoplasm,
ExpressionMelanoma,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human BATF. AA range:10-59
Gene NameBATF
DilutionImmunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Backgroundbasic leucine zipper ATF-like transcription factor(BATF) Homo sapiens The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-70454-Conjugate. Price: $485 / Size: 100μl.
E20-70454-FITC$485 / 100μlE20-70454-Biotin$485 / 100μlE20-70454-HRP$485 / 100μlE20-70454-AP$485 / 100μlE20-70454-AF350$485 / 100μlE20-70454-AF405M$485 / 100μlE20-70454-AF488$485 / 100μlE20-70454-AF514$485 / 100μlE20-70454-AF532$485 / 100μlE20-70454-AF555$485 / 100μlE20-70454-AF568$485 / 100μlE20-70454-AF405S$485 / 100μlE20-70454-AF405L$485 / 100μlE20-70454-AF546$485 / 100μlE20-70454-AF594$485 / 100μlE20-70454-AF610$485 / 100μlE20-70454-AF635$485 / 100μlE20-70454-AF647$485 / 100μlE20-70454-AF680$485 / 100μlE20-70454-AF700$485 / 100μlE20-70454-AF750$485 / 100μlE20-70454-AF790$485 / 100μlE20-70454-APC$485 / 100μlE20-70454-PE$485 / 100μlE20-70454-Cy3$485 / 100μlE20-70454-Cy5$485 / 100μlE20-70454-Cy5.5$485 / 100μlE20-70454-Cy7$485 / 100μlE20-70454-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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