ATG4A Polyclonal Antibody

Name: ATG4A Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-70393
Price: 225 USD
Availability: InStock

E20-70393Cite ID: EN0050526Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenSynthesized peptide derived from human ATG4A Polyclonal

Gene NameATG4A APG4A AUTL2

DilutionWB 1:500-2000, ELISA 1:10000-20000

Product Information

Protein NameCysteine protease ATG4A (EC 3.4.22.-) (AUT-like 2 cysteine endopeptidase) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (Autophagy-related protein 4 homolog A) (hAPG4A)

Human Gene Id115201

Human Swiss Prot NoQ8WYN0

Mouse Gene Id666468

Mouse Swiss Prot NoQ8C9S8

SpecificityThis antibody detects endogenous levels of ATG4A.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameCysteine protease ATG4A (EC 3.4.22.-) (AUT-like 2 cysteine endopeptidase) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (Autophagy-related protein 4 homolog A) (hAPG4A)Observed Band:40KD

Functionenzyme regulation:Inhibited by N-ethylmaleimide.,function:Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.,similarity:Belongs to the peptidase C54 family.,tissue specificity:Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.,

Subcellular Locationcytoplasm,cytosol,

ExpressionEpithelium,Kidney,Ovary,Prostate,Testis,,

Backgroundautophagy related 4A cysteine peptidase(ATG4A) Homo sapiens Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq, Mar 2016],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-70393-Conjugate. Price: $485 / Size: 100μl.

E20-70393-FITC$485 / 100μlE20-70393-Biotin$485 / 100μlE20-70393-HRP$485 / 100μlE20-70393-AP$485 / 100μlE20-70393-AF350$485 / 100μlE20-70393-AF405M$485 / 100μlE20-70393-AF488$485 / 100μlE20-70393-AF514$485 / 100μlE20-70393-AF532$485 / 100μlE20-70393-AF555$485 / 100μlE20-70393-AF568$485 / 100μlE20-70393-AF405S$485 / 100μlE20-70393-AF405L$485 / 100μlE20-70393-AF546$485 / 100μlE20-70393-AF594$485 / 100μlE20-70393-AF610$485 / 100μlE20-70393-AF635$485 / 100μlE20-70393-AF647$485 / 100μlE20-70393-AF680$485 / 100μlE20-70393-AF700$485 / 100μlE20-70393-AF750$485 / 100μlE20-70393-AF790$485 / 100μlE20-70393-APC$485 / 100μlE20-70393-PE$485 / 100μlE20-70393-Cy3$485 / 100μlE20-70393-Cy5$485 / 100μlE20-70393-Cy5.5$485 / 100μlE20-70393-Cy7$485 / 100μlE20-70393-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.