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ATF-5 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70388

  • Amount:

    100ul

  • Molecular Weight:

    30690DaObserved Band:31KD

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human ATF5. AA range:221-270

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using ATF-5 Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    ATF5

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

  • Protein Name:

    Cyclic AMP-dependent transcription factor ATF-5

  • Human Gene Id:

    22809

  • Human Swiss Prot No:

    Q9Y2D1

  • Mouse Gene Id:

    107503

  • Mouse Swiss Prot No:

    O70191

  • Rat Gene Id:

    282840

  • Rat Swiss Prot No:

    Q6P788

  • Specificity:

    ATF-5 Polyclonal Antibody detects endogenous levels of ATF-5 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx

  • Background:

    function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,

  • Function:

    function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3, but not with CCND1 or CCND2.,

  • Subcellular Location:

    Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis, translocates from the centrosome to the midbody. .

  • Expression:

    Widely expressed with higher expression levels in liver.

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Catalog Number

  • Amount:100ul
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ATF-5 Polyclonal Antibody | EnoGene Biotech Co. Ltd