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Cell Signal Transduction Research Antibodies
ARPP-21 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight89196Da
Protein NamecAMP-regulated phosphoprotein 21
Human Gene Id10777
Human Swiss Prot NoQ9UBL0
Mouse Gene Id74100
Mouse Swiss Prot NoQ9DCB4
SpecificityARPP-21 Polyclonal Antibody detects endogenous levels of ARPP-21 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameARPP21; TARPP; cAMP-regulated phosphoprotein 21; ARPP-21; Thymocyte cAMP-regulated phosphoprotein
Observed Band(KD)80
Functionfunction:Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.,PTM:Isoform 1 is methylated by CARM1 in immature thymocytes.,PTM:Phosphorylation at Ser-56 favors interaction with CALM1.,similarity:Contains 1 R3H domain.,subunit:Interacts with CALM1.,tissue specificity:Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level).,
Subcellular Locationcytoplasm,
ExpressionBrain,Caudate nucleus,Hypothalamus,Kidney,Lung,T-cell,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ARPP21. AA range:211-260
Gene NameARPP21
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
BackgroundcAMP regulated phosphoprotein 21(ARPP21) Homo sapiens This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],
Conjugated Antibody
This product is also available conjugated. Format: E20-70337-Conjugate. Price: $485 / Size: 100μl.
E20-70337-FITC$485 / 100μlE20-70337-Biotin$485 / 100μlE20-70337-HRP$485 / 100μlE20-70337-AP$485 / 100μlE20-70337-AF350$485 / 100μlE20-70337-AF405M$485 / 100μlE20-70337-AF488$485 / 100μlE20-70337-AF514$485 / 100μlE20-70337-AF532$485 / 100μlE20-70337-AF555$485 / 100μlE20-70337-AF568$485 / 100μlE20-70337-AF405S$485 / 100μlE20-70337-AF405L$485 / 100μlE20-70337-AF546$485 / 100μlE20-70337-AF594$485 / 100μlE20-70337-AF610$485 / 100μlE20-70337-AF635$485 / 100μlE20-70337-AF647$485 / 100μlE20-70337-AF680$485 / 100μlE20-70337-AF700$485 / 100μlE20-70337-AF750$485 / 100μlE20-70337-AF790$485 / 100μlE20-70337-APC$485 / 100μlE20-70337-PE$485 / 100μlE20-70337-Cy3$485 / 100μlE20-70337-Cy5$485 / 100μlE20-70337-Cy5.5$485 / 100μlE20-70337-Cy7$485 / 100μlE20-70337-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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