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APOBEC3A Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70270

  • Amount:

    100ul

  • Molecular Weight:

    23012Da

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human APOBEC3A. AA range:27-76

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of Jurkat cells using APOBEC3A Polyclonal Antibody

  • Gene Name:

    APOBEC3A

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Probable DNA dC->dU-editing enzyme APOBEC-3A

  • Human Gene Id:

    200315

  • Human Swiss Prot No:

    P31941

  • Specificity:

    APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1

  • Observed Band(KD):

    26

  • Background:

    apolipoprotein B mRNA editing enzyme catalytic subunit 3A(APOBEC3A) Homo sapiens This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b

  • Function:

    cofactor:Zinc.,function:Lacks cytidine deaminase activity, at least on RNA molecules (monomeric nucleoside substrates or synthetic apoB RNA template). Unable to reduce HIV-1 infectivity in vitro.,miscellaneous:It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,tissue specificity:Expressed in peripherical leukocytes and keratinocytes.,

  • Subcellular Location:

    nucleus,nucleoplasm,cytoplasm,

  • Expression:

    Brain,Keratinocyte,

  • Western blot analysis of lysates from Jurkat cells, using APOBEC3A Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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APOBEC3A Polyclonal Antibody | EnoGene Biotech Co. Ltd