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Cell Signal Transduction Research Antibodies
ApoA-V Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight41213DaObserved Band:41KD
Protein NameApolipoprotein A-V
Human Gene Id116519
Human Swiss Prot NoQ6Q788
Mouse Swiss Prot NoQ8C7G5
SpecificityApoA-V Polyclonal Antibody detects endogenous levels of ApoA-V protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameAPOA5; RAP3; Apolipoprotein A-V; Apo-AV; ApoA-V; Apolipoprotein A5; Regeneration-associated protein 3
Functioncaution:It is uncertain whether Met-1 or Met-4 is the initiator.,disease:Defects in APOA5 are a cause of hyperlipoproteinemia type 5 [MIM:144650]. Hyperlipoproteinemia type 5 is characterized by increased amounts of chylomicrons and very low density lipoprotein (VLDL) and decreased low density lipoprotein (LDL) and high density lipoprotein (HDL) in the plasma after a fast. Numerous conditions cause this phenotype, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A (GSD1A) [MIM:232200].,disease:Defects in APOA5 are a cause of susceptibility to familial hypertriglyceridemia [MIM:145750]. It is a coronary heart disease risk factor. On a regular diet the patient demonstrates increased plasma VLDL. Plasma triglycerides are persistently increased, while plasma cholesterol and phospholipids are usually within normal limits.
Subcellular Locationextracellular region,extracellular space,very-low-density lipoprotein particle,low-density lipoprotein particle,high-density lipoprotein particle,chylomicron,blood microparticle,
ExpressionLiver,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
ImmunogenSynthesized peptide derived from ApoA-V . at AA range: 30-110
Gene NameAPOA5
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Backgroundapolipoprotein A5(APOA5) Homo sapiens The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-70269-Conjugate. Price: $485 / Size: 100μl.
E20-70269-FITC$485 / 100μlE20-70269-Biotin$485 / 100μlE20-70269-HRP$485 / 100μlE20-70269-AP$485 / 100μlE20-70269-AF350$485 / 100μlE20-70269-AF405M$485 / 100μlE20-70269-AF488$485 / 100μlE20-70269-AF514$485 / 100μlE20-70269-AF532$485 / 100μlE20-70269-AF555$485 / 100μlE20-70269-AF568$485 / 100μlE20-70269-AF405S$485 / 100μlE20-70269-AF405L$485 / 100μlE20-70269-AF546$485 / 100μlE20-70269-AF594$485 / 100μlE20-70269-AF610$485 / 100μlE20-70269-AF635$485 / 100μlE20-70269-AF647$485 / 100μlE20-70269-AF680$485 / 100μlE20-70269-AF700$485 / 100μlE20-70269-AF750$485 / 100μlE20-70269-AF790$485 / 100μlE20-70269-APC$485 / 100μlE20-70269-PE$485 / 100μlE20-70269-Cy3$485 / 100μlE20-70269-Cy5$485 / 100μlE20-70269-Cy5.5$485 / 100μlE20-70269-Cy7$485 / 100μlE20-70269-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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