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APLF Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70266
  • Amount:

    100ul
  • Molecular Weight:

    56956Da
  • Price:

    225$
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human APLF. AA range:82-131
  • Source:

    Polyclonal, Rabbit
  • Western Blot analysis of HT-29 cells using APLF Polyclonal Antibody
  • Gene Name:

    APLF
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
  • Protein Name:

    Aprataxin and PNK-like factor
  • Human Gene Id:

    200558
  • Human Swiss Prot No:

    Q8IW19
  • Specificity:

    APLF Polyclonal Antibody detects endogenous levels of APLF protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    APLF; C2orf13; PALF; XIP1; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1
  • Observed Band(KD):

    57
  • Background:

    aprataxin and PNKP like factor(APLF) Homo sapiens C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008],
  • Function:

    domain:The FHA-like domain mediates interaction with XRCC1 and XRCC4.,function:Involved in single-strand and double-strand DNA break repair.,PTM:Phosphorylated in an ATM-dependent manner upon double-strand DNA break.,similarity:Contains 1 FHA-like domain.,similarity:Contains 2 C2H2-type zinc fingers.,subcellular location:Colocalizes with XRCC1 at sites of DNA damage.,subunit:Interacts with XRCC1. May also interact with XRCC4 and XRCC5.,
  • Subcellular Location:

    nucleus,nucleoplasm,cytosol,site of double-strand break,
  • Expression:

    Testis,
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using APLF Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

Add to Cart

AbPromise
APLF Polyclonal Antibody | EnoGene Biotech Co. Ltd