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APLNR Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70265

  • Amount:

    100ul

  • Molecular Weight:

    42660Da

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human AGTRL1. AA range:141-190

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of 293 cells using APLNR Polyclonal Antibody

  • Gene Name:

    APLNR

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Apelin receptor

  • Human Gene Id:

    187

  • Human Swiss Prot No:

    P35414

  • Specificity:

    APLNR Polyclonal Antibody detects endogenous levels of APLNR protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    APLNR; AGTRL1; APJ; Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11

  • Observed Band(KD):

    43

  • Background:

    apelin receptor(APLNR) Homo sapiens This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009],

  • Function:

    function:Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.,

  • Subcellular Location:

    plasma membrane,integral component of plasma membrane,integral component of membrane,

  • Expression:

    Brain,Placenta,Thyroid gland,Whole embryo,

  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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APLNR Polyclonal Antibody | EnoGene Biotech Co. Ltd