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APC1 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70260

  • Amount:

    100ul

  • Molecular Weight:

    216500Da

  • Applications:

    WB;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human ANAPC1. AA range:1311-1360

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using APC1 Polyclonal Antibody

  • Gene Name:

    ANAPC1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Anaphase-promoting complex subunit 1

  • Human Gene Id:

    64682

  • Human Swiss Prot No:

    Q9H1A4

  • Mouse Gene Id:

    17222

  • Mouse Swiss Prot No:

    P53995

  • Specificity:

    APC1 Polyclonal Antibody detects endogenous levels of APC1 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    ANAPC1; TSG24; Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein

  • Observed Band(KD):

    215

  • Background:

    This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011],

  • Function:

    function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis.,similarity:Belongs to the APC1 family.,similarity:Contains 4 PC repeats.,subunit:The APC/C is composed of at least 11 subunits.,

  • Subcellular Location:

    nucleoplasm,anaphase-promoting complex,cytosol,

  • Expression:

    Colon,Epithelium,Ovary,Placenta,

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Catalog Number

  • Amount:100ul
  • Price:225$

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APC1 Polyclonal Antibody | EnoGene Biotech Co. Ltd