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AP-2γ Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70254

  • Amount:

    100ul

  • Molecular Weight:

    49177Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human AP2C. AA range:401-450

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using AP-2γ Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit

  • Gene Name:

    TFAP2C

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

  • Background:

    transcription factor AP-2 gamma(TFAP2C) Homo sapiens The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Transcription factor AP-2 gamma

  • Human Gene Id:

    7022

  • Human Swiss Prot No:

    Q92754

  • Mouse Gene Id:

    21420

  • Mouse Swiss Prot No:

    Q61312

  • Specificity:

    AP-2γ Polyclonal Antibody detects endogenous levels of AP-2γ protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    TFAP2C; Transcription factor AP-2 gamma; AP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1

  • Observed Band(KD):

    45

  • Function:

    domain:The WW-binding motif mediates interaction with WWOX.,function:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.,induction:During retinoic acid-mediated differentiation.,online information:Activatin protein 2 entry,PTM:Sumoylated on Lys-10; which inhibits transcriptional activity.,similarity:Belongs to the AP-2 family.,subunit:Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I

  • Subcellular Location:

    Nucleus .

  • Expression:

    Liver,Mammary tumor,Ovary,Skin,

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Catalog Number

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AP-2γ Polyclonal Antibody | EnoGene Biotech Co. Ltd