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AOX1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70243Amount:
100ulMolecular Weight:
147931DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human AOX1. AA range:521-570Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using AOX1 Polyclonal Antibody diluted at 1:2000
Gene Name:
AOX1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.Background:
Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008],Protein Name:
Aldehyde oxidaseHuman Gene Id:
316Human Swiss Prot No:
Q06278Mouse Swiss Prot No:
O54754Rat Gene Id:
54349Rat Swiss Prot No:
Q9Z0U5Specificity:
AOX1 Polyclonal Antibody detects endogenous levels of AOX1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
AOX1; AO; Aldehyde oxidaseObserved Band(KD):
120Function:
catalytic activity:An aldehyde + H(2)O + O(2) = a carboxylic acid + H(2)O(2).,caution:Was originally (PubMed:8248161) thought to be a xanthine dehydrogenase.,cofactor:Binds 2 2Fe-2S clusters.,cofactor:FAD.,cofactor:Molybdopterin.,similarity:Belongs to the xanthine dehydrogenase family.,similarity:Contains 1 2Fe-2S ferredoxin-type domain.,similarity:Contains 1 FAD-binding PCMH-type domain.,subunit:Homodimer.,tissue specificity:Abundant in liver, lower levels in lung, skeletal muscle, pancreas. Undetected in heart, brain and kidney.,Subcellular Location:
Cytoplasm .Expression:
Abundant in liver, expressed in adipose tissue and at lower levels in lung, skeletal muscle, pancreas. In contrast to mice, no significant gender difference in AOX1 expression level (at protein level).
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