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Amylin Polyclonal Antibody
Datasheet
Catalog Number:
E20-70225Amount:
100ulMolecular Weight:
9806DaApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Rat;Mouse;Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human Amylin. AA range:1-50Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using Amylin Polyclonal Antibody diluted at 1:1000
Gene Name:
IAPPDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.Background:
islet amyloid polypeptide(IAPP) Homo sapiens This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016],Protein Name:
Islet amyloid polypeptideHuman Gene Id:
3375Human Swiss Prot No:
P10997Mouse Swiss Prot No:
P12968Specificity:
Amylin Polyclonal Antibody detects endogenous levels of Amylin protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
IAPP; Islet amyloid polypeptide; Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptideObserved Band(KD):
25Function:
disease:IAPP is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.,function:Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.,online information:Amylin entry,similarity:Belongs to the calcitonin family.,Subcellular Location:
Secreted .
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