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AMPD2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70212Amount:
100ulMolecular Weight:
100688DaApplications:
WB;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human AMPD2. AA range:131-180Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using AMPD2 Polyclonal Antibody
Gene Name:
AMPD2Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.Background:
The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],Protein Name:
AMP deaminase 2Human Gene Id:
271Human Swiss Prot No:
Q01433Mouse Gene Id:
109674Mouse Swiss Prot No:
Q9DBT5Rat Gene Id:
362015Rat Swiss Prot No:
Q02356Specificity:
AMPD2 Polyclonal Antibody detects endogenous levels of AMPD2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
AMPD2; AMP deaminase 2; AMP deaminase isoform LObserved Band(KD):
100Function:
catalytic activity:AMP + H(2)O = IMP + NH(3).,function:AMP deaminase plays a critical role in energy metabolism.,pathway:Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.,similarity:Belongs to the adenosine and AMP deaminases family.,subunit:Homotetramer.,tissue specificity:Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes.,Subcellular Location:
cytosol,Expression:
Highly expressed in cerebellum.
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