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ALDH1B1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70189Amount:
100ulMolecular Weight:
57238DaApplications:
WB;ELISAReactivity:
Human;MonkeyPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human ALDH1B1. AA range:311-360Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of COS7 cells using ALDH1B1 Polyclonal Antibody diluted at 1:1000
Gene Name:
ALDH1B1Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.Background:
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008],Protein Name:
Aldehyde dehydrogenase X mitochondrialHuman Gene Id:
219Human Swiss Prot No:
P30837Mouse Swiss Prot No:
Q9CZS1Specificity:
ALDH1B1 Polyclonal Antibody detects endogenous levels of ALDH1B1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ALDH1B1; ALDH5; ALDHX; Aldehyde dehydrogenase X; mitochondrial; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1Observed Band(KD):
57Function:
catalytic activity:An aldehyde + NAD(+) + H(2)O = an acid + NADH.,function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer.,tissue specificity:Liver, testis and to a lesser extent in brain.,Subcellular Location:
Mitochondrion matrix.Expression:
Liver, testis and to a lesser extent in brain.
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