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AKR1A1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70171Amount:
100ulMolecular Weight:
36575DaApplications:
：WB;ELISAReactivity:
：Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human AKR1CL2. AA range:141-190Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using AKR1CL2 Polyclonal Antibody diluted at 1:500
Gene Name:
AKR1E2Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.Background:
The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],Protein Name:
1,5-anhydro-D-fructose reductaseHuman Gene Id:
83592Human Swiss Prot No:
Q96JD6Mouse Swiss Prot No:
Q9DCT1Specificity:
AKR1CL2 Polyclonal Antibody detects endogenous levels of AKR1CL2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
AKR1E2; AKR1CL2; AKRDC1; 1; 5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis-specific protein; hTSPObserved Band(KD):
37Function:
catalytic activity:1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.,function:Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Testis-specific.,Subcellular Location:
Cytoplasm .Expression:
Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078).
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