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AKR1A1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70169Amount:
100ulMolecular Weight:
36573DaApplications:
WB;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
Synthesized peptide derived from AKR1A1 . at AA range: 250-330Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of NIH-3T3 cells using AKR1A1 Polyclonal Antibody
Gene Name:
AKR1A1Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011],Protein Name:
Alcohol dehydrogenase [NADP(+)]Human Gene Id:
10327Human Swiss Prot No:
P14550Mouse Gene Id:
58810Mouse Swiss Prot No:
Q9JII6Rat Gene Id:
78959Rat Swiss Prot No:
P51635Specificity:
AKR1A1 Polyclonal Antibody detects endogenous levels of AKR1A1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
AKR1A1; ALDR1; ALR; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1Observed Band(KD):
37Function:
catalytic activity:An alcohol + NADP(+) = an aldehyde + NADPH.,function:Catalyzes the NADPH-dependent reduction of a variety of aldehydes to their corresponding alcohols.,similarity:Belongs to the aldo/keto reductase family.,subunit:Monomer.,Subcellular Location:
Cytoplasm, cytosol . Apical cell membrane .Expression:
Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
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