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Cell Signal Transduction Research Antibodies

AKAP 220 Polyclonal Antibody

E20-70165Cite ID: EN0050298DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight210512Da
Protein NameA-kinase anchor protein 11
Human Gene Id11215
Human Swiss Prot NoQ9UKA4
SpecificityAKAP 220 Polyclonal Antibody detects endogenous levels of AKAP 220 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameAKAP11; AKAP220; KIAA0629; A-kinase anchor protein 11; AKAP-11; A-kinase anchor protein 220 kDa; AKAP 220; hAKAP220; Protein kinase A-anchoring protein 11; PRKA11
Functiondomain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Binds to type II regulatory subunits of protein kinase A and anchors/targets them.,similarity:Belongs to the AKAP110 family.,subcellular location:Cytoplasmic in premeiotic pachytene spermatocytes and in the centrosome of developing postmeiotic germ cells, while a midpiece/centrosome localization was found in elongating spermatocytes and mature sperm.,tissue specificity:Expressed in heart, brain, lung, liver, kidney, testis and ovary. Weakly expressed in skeletal muscle, pancreas and spleen.,
Subcellular Locationperoxisome,microtubule organizing center,
ExpressionBrain,Cerebral cortex,Placenta,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human AKAP11. AA range:1761-1810
Gene NameAKAP11
DilutionImmunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundA-kinase anchoring protein 11(AKAP11) Homo sapiens The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-70165-Conjugate. Price: $485 / Size: 100μl.

E20-70165-FITC$485 / 100μlE20-70165-Biotin$485 / 100μlE20-70165-HRP$485 / 100μlE20-70165-AP$485 / 100μlE20-70165-AF350$485 / 100μlE20-70165-AF405M$485 / 100μlE20-70165-AF488$485 / 100μlE20-70165-AF514$485 / 100μlE20-70165-AF532$485 / 100μlE20-70165-AF555$485 / 100μlE20-70165-AF568$485 / 100μlE20-70165-AF405S$485 / 100μlE20-70165-AF405L$485 / 100μlE20-70165-AF546$485 / 100μlE20-70165-AF594$485 / 100μlE20-70165-AF610$485 / 100μlE20-70165-AF635$485 / 100μlE20-70165-AF647$485 / 100μlE20-70165-AF680$485 / 100μlE20-70165-AF700$485 / 100μlE20-70165-AF750$485 / 100μlE20-70165-AF790$485 / 100μlE20-70165-APC$485 / 100μlE20-70165-PE$485 / 100μlE20-70165-Cy3$485 / 100μlE20-70165-Cy5$485 / 100μlE20-70165-Cy5.5$485 / 100μlE20-70165-Cy7$485 / 100μlE20-70165-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.