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AKAP 14 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70162

  • Amount:

    100ul

  • Molecular Weight:

    22815Da

  • Reactivity:

    Human,Mouse,Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human AKAP14. AA range:1-50

  • Source:

    Polyclonal, Rabbit

  • Immunofluorescence analysis of HeLa cells, using AKAP14 Antibody. The picture on the right is blocked with the synthesized peptide.

  • Gene Name:

    AKAP14

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Protein Name:

    A-kinase anchor protein 14

  • Human Gene Id:

    158798

  • Human Swiss Prot No:

    Q86UN6

  • Specificity:

    AKAP 14 Polyclonal Antibody detects endogenous levels of AKAP 14 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    AKAP14; AKAP28; A-kinase anchor protein 14; AKAP-14; A-kinase anchor protein 28 kDa; AKAP 28; Protein kinase A-anchoring protein 14; PRKA14

  • Observed Band(KD):

    23

  • Background:

    A-kinase anchoring protein 14(AKAP14) Homo sapiens The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

  • Function:

    caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Binds to type II regulatory subunits of protein kinase A and anchors/targets them.,subunit:Binds to type II regulatory subunits (RII).,tissue specificity:Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.,

  • Subcellular Location:

    cytoplasm,

  • Western Blot analysis of Jurkat cells using AKAP 14 Polyclonal Antibody

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