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AIM2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70151

  • Amount:

    100ul

  • Molecular Weight:

    38954Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human; Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human AIM2. AA range:51-100

  • Source:

    Polyclonal, Rabbit,IgG

  • Western blot analysis of lysates from HUVEC cells, using AIM2 Antibody. The lane on the right is blocked with the synthesized peptide.

  • Gene Name:

    AIM2

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

  • Background:

    AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Interferon-inducible protein AIM2

  • Human Gene Id:

    9447

  • Human Swiss Prot No:

    O14862

  • Mouse Swiss Prot No:

    Q91VJ1

  • Specificity:

    AIM2 Polyclonal Antibody detects endogenous levels of AIM2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2

  • Observed Band(KD):

    39

  • Function:

    disease:Defects in AIM2 may be a cause of microsatellite unstable colon cancers.,function:Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.,induction:By interferon gamma.,similarity:Belongs to the HIN-200 family.,similarity:Contains 1 DAPIN domain.,similarity:Contains 1 HIN-200 domain.,subunit:Homodimer.,tissue specificity:Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.,

  • Subcellular Location:

    Nucleus. Cytoplasm. Activated inflammasomes can aggregate in the cytosol as speck-like particles.

  • Expression:

    Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.

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Catalog Number

  • Amount:100ul
  • Price:225$

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AIM2 Polyclonal Antibody | EnoGene Biotech Co. Ltd