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AIFL Polyclonal Antibody
Datasheet
Catalog Number:
E20-70148Amount:
100ulMolecular Weight:
66791DaApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using AIFL Polyclonal Antibody
Gene Name:
AIFM3Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.Background:
domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,Protein Name:
Apoptosis-inducing factor 3Human Gene Id:
150209Human Swiss Prot No:
Q96NN9Mouse Gene Id:
72168Mouse Swiss Prot No:
Q3TY86Specificity:
AIFL Polyclonal Antibody detects endogenous levels of AIFL protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like proteinObserved Band(KD):
67Function:
domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,Subcellular Location:
Mitochondrion . Does not translocate to the nucleus upon induction of apoptosis.Expression:
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
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