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AHA-1 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70146

  • Amount:

    100ul

  • Molecular Weight:

    38274Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human AHSA1. AA range:161-210

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using AHA-1 Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    AHSA1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

  • Background:

    function:Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.,induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG).,similarity:Belongs to the AHA1 family.,subcellular location:May transiently interact with the endoplasmic reticulum.,subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1.,tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.,

  • Protein Name:

    Activator of 90 kDa heat shock protein ATPase homolog 1

  • Human Gene Id:

    10598

  • Human Swiss Prot No:

    O95433

  • Mouse Swiss Prot No:

    Q8BK64

  • Specificity:

    AHA-1 Polyclonal Antibody detects endogenous levels of AHA-1 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38

  • Observed Band(KD):

    38

  • Function:

    function:Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.,induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG).,similarity:Belongs to the AHA1 family.,subcellular location:May transiently interact with the endoplasmic reticulum.,subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1.,tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.,

  • Subcellular Location:

    Cytoplasm, cytosol . Endoplasmic reticulum . May transiently interact with the endoplasmic reticulum.

  • Expression:

    Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.

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Catalog Number

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