World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
ADK Polyclonal Antibody Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight40545Da
Protein NameAdenosine kinase
Human Gene Id132
Human Swiss Prot NoP55263
Mouse Gene Id11534
Mouse Swiss Prot NoP55264
Rat Gene Id25368
Rat Swiss Prot NoQ64640
SpecificityADK Polyclonal Antibody detects endogenous levels of ADK protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameADK; Adenosine kinase; AK; Adenosine 5'-phosphotransferase
Observed Band(KD)40
Functioncatalytic activity:ATP + adenosine = ADP + AMP.,cofactor:Binds 3 magnesium ions per subunit.,function:ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.,pathway:Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.,similarity:Belongs to the carbohydrate kinase pfkB family.,subunit:Monomer.,tissue specificity:Widely expressed. Highest level in placenta, liver, muscle and kidney.,
Subcellular Locationnucleus,nucleoplasm,cytoplasm,cytosol,
ExpressionLiver,Skin,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ADK. AA range:1-50
Gene NameADK
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundadenosine kinase(ADK) Homo sapiens This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-70135-Conjugate. Price: $485 / Size: 100μl.
E20-70135-FITC$485 / 100μlE20-70135-Biotin$485 / 100μlE20-70135-HRP$485 / 100μlE20-70135-AP$485 / 100μlE20-70135-AF350$485 / 100μlE20-70135-AF405M$485 / 100μlE20-70135-AF488$485 / 100μlE20-70135-AF514$485 / 100μlE20-70135-AF532$485 / 100μlE20-70135-AF555$485 / 100μlE20-70135-AF568$485 / 100μlE20-70135-AF405S$485 / 100μlE20-70135-AF405L$485 / 100μlE20-70135-AF546$485 / 100μlE20-70135-AF594$485 / 100μlE20-70135-AF610$485 / 100μlE20-70135-AF635$485 / 100μlE20-70135-AF647$485 / 100μlE20-70135-AF680$485 / 100μlE20-70135-AF700$485 / 100μlE20-70135-AF750$485 / 100μlE20-70135-AF790$485 / 100μlE20-70135-APC$485 / 100μlE20-70135-PE$485 / 100μlE20-70135-Cy3$485 / 100μlE20-70135-Cy5$485 / 100μlE20-70135-Cy5.5$485 / 100μlE20-70135-Cy7$485 / 100μlE20-70135-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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