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Cell Signal Transduction Research Antibodies
Adenosine A2A-R Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight44707Da
Protein NameAdenosine receptor A2a
Human Gene Id135
Human Swiss Prot NoP29274
Mouse Swiss Prot NoQ60613
SpecificityAdenosine A2A-R Polyclonal Antibody detects endogenous levels of Adenosine A2A-R protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameADORA2A; ADORA2; Adenosine receptor A2a
Observed Band(KD)45
Functionfunction:Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Locationintermediate filament,plasma membrane,integral component of plasma membrane,endomembrane system,postsynaptic density,membrane,integral component of membrane,dendrite,axolemma,asymmetric synapse,presynaptic membrane,neuronal cell
ExpressionBrain,Hippocampus,Lymph,Thymus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ADORA2A. AA range:321-370
Gene NameADORA2A
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Backgroundadenosine A2a receptor(ADORA2A) Homo sapiens This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript compos
Conjugated Antibody
This product is also available conjugated. Format: E20-70130-Conjugate. Price: $485 / Size: 100μl.
E20-70130-FITC$485 / 100μlE20-70130-Biotin$485 / 100μlE20-70130-HRP$485 / 100μlE20-70130-AP$485 / 100μlE20-70130-AF350$485 / 100μlE20-70130-AF405M$485 / 100μlE20-70130-AF488$485 / 100μlE20-70130-AF514$485 / 100μlE20-70130-AF532$485 / 100μlE20-70130-AF555$485 / 100μlE20-70130-AF568$485 / 100μlE20-70130-AF405S$485 / 100μlE20-70130-AF405L$485 / 100μlE20-70130-AF546$485 / 100μlE20-70130-AF594$485 / 100μlE20-70130-AF610$485 / 100μlE20-70130-AF635$485 / 100μlE20-70130-AF647$485 / 100μlE20-70130-AF680$485 / 100μlE20-70130-AF700$485 / 100μlE20-70130-AF750$485 / 100μlE20-70130-AF790$485 / 100μlE20-70130-APC$485 / 100μlE20-70130-PE$485 / 100μlE20-70130-Cy3$485 / 100μlE20-70130-Cy5$485 / 100μlE20-70130-Cy5.5$485 / 100μlE20-70130-Cy7$485 / 100μlE20-70130-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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