Product Information
Molecular Weight36512Da
Protein NameAdenosine receptor A1
Human Gene Id134
Human Swiss Prot NoP30542
Mouse Swiss Prot NoQ60612
Rat Gene Id29290
Rat Swiss Prot NoP25099
SpecificityAdenosine A1-R Polyclonal Antibody detects endogenous levels of Adenosine A1-R protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameADORA1; Adenosine receptor A1
Observed Band(KD)37
Functionfunction:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Locationendoplasmic reticulum,plasma membrane,integral component of plasma membrane,postsynaptic density,integral component of membrane,basolateral plasma membrane,axolemma,asymmetric synapse,presynaptic membrane,neuronal cell body,terminal bouton
ExpressionBrain,Heart,Hippocampus,
Backgroundadenosine A1 receptor(ADORA1) Homo sapiens The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008],