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Actin-α/γ Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70104

  • Amount:

    100ul

  • Swiss-Prot No.:

    P68032/P63261/P63267/P68133 P68035/P63259/P63269/P68136

  • Molecular Weight:

    41737/41793，Observed Band : 45kd

  • Price:

    225$

  • Applications:

    WB,IHC-p,IF/ICC,ELISA

  • Reactivity:

    Human,Mouse,Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinitychromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human
    Actin. AA range:21-70

  • Specificity/Sensitivity:

    Actin-α/γ Polyclonal Antibody detects endogenous levels of Actin-α/γ protein.

  • Storage/Stability:

    -20°C/1 year

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    ACTC1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300.Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other

  • Immunofluorescence analysis of HUVEC cells, using Actin-pan Antibody. The picture on the right is blocked with the synthesized peptide.

  • Background:

    actin, alpha, cardiac muscle 1(ACTC1) Homo sapiens Actins are highly
    conserved proteins that are involved in various types of cell motility.
    Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in
    the form of a two-stranded helix. Each actin can bind to four others. The protein
    encoded by this gene belongs to the actin family which is comprised of three main
    groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in
    muscle tissues and are a major constituent of the contractile apparatus. Defects
    in this gene have been associated with idiopathic dilated cardiomyopathy (IDC)
    and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]

  • Gene ID:

    58/70/71/72 11464/11465/11468/11459 29275/100361457/25365/29437

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

  • Function:

    disease:Defects in ACTC1 are the cause of cardiomyopathy dilated type 1R(CMD1R) [MIM:102540]. Dilated cardiomyopathy is a disorder characterized byventricular dilation and impaired systolic function, resulting in congestive heartfailure and arrhythmia. Patients are at risk of premature death.,disease:Defects inACTC1 are the cause of cardiomyopathy familial hypertrophic type 11 (CMH11)[MIM:612098]. Familial hypertrophic cardiomyopathy is a hereditary heartdisorder characterized by ventricular hypertrophy, which is usually asymmetricand often involves the interventricular septum. The symptoms include dyspnea,syncope, collapse, palpitations, and chest pain. They can be readily provoked byexercise. The disorder has inter- and intrafamilial variability ranging from benignto malignant forms with high risk of cardiac failure and sudden cardiacdeath.,function:Actins are highly conserv

  • Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Actin-pan Antibody. The picture on the right is blocked with the synthesized peptide.

  • Western blot analysis of lysates from mouse brain, using Actin pan Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
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Actin-α/γ Polyclonal Antibody | EnoGene Biotech Co. Ltd