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Cell Signal Transduction Research Antibodies
ACSVL6 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight75385Da
Protein NameBile acyl-CoA synthetase
Human Gene Id10998
Human Swiss Prot NoQ9Y2P5
Mouse Swiss Prot NoQ4LDG0
SpecificityACSVL6 Polyclonal Antibody detects endogenous levels of ACSVL6 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC27A5; ACSB; ACSVL6; FACVL3; FATP5; Bile acyl-CoA synthetase; BACS; Bile acid-CoA ligase; BA-CoA ligase; BAL; Cholate--CoA ligase; Fatty acid transport protein 5; FATP-5; Fatty-acid-coenzyme A ligase; very long-chain 3; Solute carrier fam
Observed Band(KD)75
Functioncatalytic activity:ATP + (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA.,catalytic activity:ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA.,function:Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,tissue specificity:Predominantly expressed in l
Subcellular Locationendoplasmic reticulum,endoplasmic reticulum membrane,basal plasma membrane,integral component of membrane,integral component of endoplasmic reticulum membrane,protein complex,
ExpressionBrain,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human SLC27A5. AA range:481-530
Gene NameSLC27A5
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundsolute carrier family 27 member 5(SLC27A5) Homo sapiens The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-70095-Conjugate. Price: $485 / Size: 100μl.
E20-70095-FITC$485 / 100μlE20-70095-Biotin$485 / 100μlE20-70095-HRP$485 / 100μlE20-70095-AP$485 / 100μlE20-70095-AF350$485 / 100μlE20-70095-AF405M$485 / 100μlE20-70095-AF488$485 / 100μlE20-70095-AF514$485 / 100μlE20-70095-AF532$485 / 100μlE20-70095-AF555$485 / 100μlE20-70095-AF568$485 / 100μlE20-70095-AF405S$485 / 100μlE20-70095-AF405L$485 / 100μlE20-70095-AF546$485 / 100μlE20-70095-AF594$485 / 100μlE20-70095-AF610$485 / 100μlE20-70095-AF635$485 / 100μlE20-70095-AF647$485 / 100μlE20-70095-AF680$485 / 100μlE20-70095-AF700$485 / 100μlE20-70095-AF750$485 / 100μlE20-70095-AF790$485 / 100μlE20-70095-APC$485 / 100μlE20-70095-PE$485 / 100μlE20-70095-Cy3$485 / 100μlE20-70095-Cy5$485 / 100μlE20-70095-Cy5.5$485 / 100μlE20-70095-Cy7$485 / 100μlE20-70095-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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