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Cell Signal Transduction Research Antibodies
ACSVL4 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight72064Da
Protein NameLong-chain fatty acid transport protein 4
Human Gene Id10999
Human Swiss Prot NoQ6P1M0
Mouse Swiss Prot NoQ91VE0
SpecificityACSVL4 Polyclonal Antibody detects endogenous levels of ACSVL4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSLC27A4; ACSVL4; FATP4; Long-chain fatty acid transport protein 4; FATP-4; Fatty acid transport protein 4; Solute carrier family 27 member 4
Functionfunction:Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.,miscellaneous:SLC27A4/FATP4-mediated fatty acid uptake is associated to paramaters related to insulin resistance, which is associated with disturbed fatty acid metabolism and homeostasis, such as obesity. SLC27A4/FATP4 expression is positively correlated with aquired obesity.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,tissue specificity:Expressed at highest levels in brain, testis, colon and kidney. Expressed at medium levels in heart and liver, small intestine and stomach. Expressed at low levels in perip
Subcellular Locationendoplasmic reticulum,endoplasmic reticulum membrane,plasma membrane,microvillus,membrane,integral component of membrane,brush border membrane,
ExpressionBrain,Heart,Lung,Skin,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human SLC27A4. AA range:61-110
Gene NameSLC27A4
DilutionImmunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundsolute carrier family 27 member 4(SLC27A4) Homo sapiens This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-70094-Conjugate. Price: $485 / Size: 100μl.
E20-70094-FITC$485 / 100μlE20-70094-Biotin$485 / 100μlE20-70094-HRP$485 / 100μlE20-70094-AP$485 / 100μlE20-70094-AF350$485 / 100μlE20-70094-AF405M$485 / 100μlE20-70094-AF488$485 / 100μlE20-70094-AF514$485 / 100μlE20-70094-AF532$485 / 100μlE20-70094-AF555$485 / 100μlE20-70094-AF568$485 / 100μlE20-70094-AF405S$485 / 100μlE20-70094-AF405L$485 / 100μlE20-70094-AF546$485 / 100μlE20-70094-AF594$485 / 100μlE20-70094-AF610$485 / 100μlE20-70094-AF635$485 / 100μlE20-70094-AF647$485 / 100μlE20-70094-AF680$485 / 100μlE20-70094-AF700$485 / 100μlE20-70094-AF750$485 / 100μlE20-70094-AF790$485 / 100μlE20-70094-APC$485 / 100μlE20-70094-PE$485 / 100μlE20-70094-Cy3$485 / 100μlE20-70094-Cy5$485 / 100μlE20-70094-Cy5.5$485 / 100μlE20-70094-Cy7$485 / 100μlE20-70094-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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