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Acrp30 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70091

  • Amount:

    100ul

  • Molecular Weight:

    26414Da

  • Applications:

    WB;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human Acrp30. AA range:6-55

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of HeLa cells using Acrp30 Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    ADIPOQ

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

  • Background:

    adiponectin, C1Q and collagen domain containing(ADIPOQ) Homo sapiens This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010],

  • Protein Name:

    Adiponectin

  • Human Gene Id:

    9370

  • Human Swiss Prot No:

    Q15848

  • Mouse Gene Id:

    11450

  • Mouse Swiss Prot No:

    Q60994

  • Specificity:

    Acrp30 Polyclonal Antibody detects endogenous levels of Acrp30 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    ADIPOQ; ACDC; ACRP30; APM1; GBP28; Adiponectin; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte; C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1

  • Observed Band(KD):

    30

  • Function:

    disease:Defects in ADIPOQ are the cause of adiponectin deficiency (ADPND) [MIM:612556]. ADPND results in very low concentrations of plasma adiponectin.,disease:Genetic variations in ADIPOQ are associated with non-insulin-dependent diabetes mellitus (NIDDM) [MIM:125853]; also known as diabetes mellitus type 2. NIDDM is characterized by an autosomal dominant mode of inheritance, onset during adulthood and insulin resistance.,domain:The C1q domain is commonly called the globular domain.,function:Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver

  • Subcellular Location:

    Secreted .

  • Expression:

    Synthesized exclusively by adipocytes and secreted into plasma.

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Catalog Number

  • Amount:100ul
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Acrp30 Polyclonal Antibody | EnoGene Biotech Co. Ltd