World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
A Cyclase VIII Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight140122Da
Protein NameAdenylate cyclase type 8
Human Gene Id114
Human Swiss Prot NoP40145
Mouse Gene Id11514
Mouse Swiss Prot NoP97490
Rat Gene Id29241
Rat Swiss Prot NoP40146
SpecificityA Cyclase VIII Polyclonal Antibody detects endogenous levels of A Cyclase VIII protein
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameADCY8; Adenylate cyclase type 8; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; AC8; Ca(2+)/calmodulin-activated adenylyl cyclase
Functioncatalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Activated by calcium/calmodulin.,function:This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains.,
Subcellular Locationintracellular,plasma membrane,membrane,integral component of membrane,
ExpressionBrain,Brain stem,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ADCY8. AA range:591-640
Gene NameADCY8
DilutionImmunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundadenylate cyclase 8(ADCY8) Homo sapiens Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-70035-Conjugate. Price: $485 / Size: 100μl.
E20-70035-FITC$485 / 100μlE20-70035-Biotin$485 / 100μlE20-70035-HRP$485 / 100μlE20-70035-AP$485 / 100μlE20-70035-AF350$485 / 100μlE20-70035-AF405M$485 / 100μlE20-70035-AF488$485 / 100μlE20-70035-AF514$485 / 100μlE20-70035-AF532$485 / 100μlE20-70035-AF555$485 / 100μlE20-70035-AF568$485 / 100μlE20-70035-AF405S$485 / 100μlE20-70035-AF405L$485 / 100μlE20-70035-AF546$485 / 100μlE20-70035-AF594$485 / 100μlE20-70035-AF610$485 / 100μlE20-70035-AF635$485 / 100μlE20-70035-AF647$485 / 100μlE20-70035-AF680$485 / 100μlE20-70035-AF700$485 / 100μlE20-70035-AF750$485 / 100μlE20-70035-AF790$485 / 100μlE20-70035-APC$485 / 100μlE20-70035-PE$485 / 100μlE20-70035-Cy3$485 / 100μlE20-70035-Cy5$485 / 100μlE20-70035-Cy5.5$485 / 100μlE20-70035-Cy7$485 / 100μlE20-70035-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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