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Cell Signal Transduction Research Antibodies

A Cyclase IX Polyclonal Antibody

E20-70031Cite ID: EN0050164DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight150701DaObserved Band:150KD
Protein NameAdenylate cyclase type 9
Human Gene Id115
Human Swiss Prot NoO60503
Mouse Swiss Prot NoP51830
SpecificityA Cyclase IX Polyclonal Antibody detects endogenous levels of A Cyclase IX protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameADCY9; KIAA0520; Adenylate cyclase type 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9
Functioncatalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Insensitive to calcium/calmodulin, forskolin and somatostatin. Stimulated by beta-adrenergic receptor activation.,function:May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains.,tissue specificity:Expressed in multiple cells of the lung, with expression highest in airway smooth muscle.,
Subcellular Locationintracellular,plasma membrane,integral component of plasma membrane,integral component of membrane,axon,dendrite,
ExpressionBrain,Epithelium,Heart,,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ADCY9. AA range:137-186
Gene NameADCY9
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Backgroundadenylate cyclase 9(ADCY9) Homo sapiens Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008],

Conjugated Antibody

This product is also available conjugated. Format: E20-70031-Conjugate. Price: $485 / Size: 100μl.

E20-70031-FITC$485 / 100μlE20-70031-Biotin$485 / 100μlE20-70031-HRP$485 / 100μlE20-70031-AP$485 / 100μlE20-70031-AF350$485 / 100μlE20-70031-AF405M$485 / 100μlE20-70031-AF488$485 / 100μlE20-70031-AF514$485 / 100μlE20-70031-AF532$485 / 100μlE20-70031-AF555$485 / 100μlE20-70031-AF568$485 / 100μlE20-70031-AF405S$485 / 100μlE20-70031-AF405L$485 / 100μlE20-70031-AF546$485 / 100μlE20-70031-AF594$485 / 100μlE20-70031-AF610$485 / 100μlE20-70031-AF635$485 / 100μlE20-70031-AF647$485 / 100μlE20-70031-AF680$485 / 100μlE20-70031-AF700$485 / 100μlE20-70031-AF750$485 / 100μlE20-70031-AF790$485 / 100μlE20-70031-APC$485 / 100μlE20-70031-PE$485 / 100μlE20-70031-Cy3$485 / 100μlE20-70031-Cy5$485 / 100μlE20-70031-Cy5.5$485 / 100μlE20-70031-Cy7$485 / 100μlE20-70031-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.