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A Cyclase IV Polyclonal Antibody
Datasheet
Catalog Number:
E20-70030Amount:
100ulMolecular Weight:
119794DaPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human ADCY4. AA range:195-244Source:
Polyclonal, Rabbit
- Western Blot analysis of Jurkat cells using A Cyclase IV Polyclonal Antibody
Gene Name:
ADCY4Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Adenylate cyclase type 4Human Gene Id:
196883Human Swiss Prot No:
Q8NFM4Specificity:
A Cyclase IV Polyclonal Antibody detects endogenous levels of A Cyclase IV protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ADCY4; Adenylate cyclase type 4; ATP pyrophosphate-lyase 4; Adenylate cyclase type IV; Adenylyl cyclase 4Observed Band(KD):
120Background:
adenylate cyclase 4(ADCY4) Homo sapiens This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010],Function:
catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Insensitive to calcium/calmodulin. Stimulated by the G protein beta and gamma subunit complex.,function:This is a membrane-bound, calmodulin-insensitive adenylyl cyclase.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains.,Subcellular Location:
intracellular,cytoplasm,plasma membrane,membrane,integral component of membrane,dendrite,Expression:
Lung,Placenta,Spleen,Testis,Uterus,
- Western blot analysis of lysates from Jurkat cells, using ADCY4 Antibody. The lane on the right is blocked with the synthesized peptide.
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Catalog Number
- Amount:100ul
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