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CNOT2 (phospho Ser101) Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-61105

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CNOT2 around the phosphorylation site of Ser101. AA range:67-116

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    CNOT2

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using CNOT2 (Phospho-Ser101) Antibody

  • Background:

    CCR4-NOT transcription complex subunit 2(CNOT2) Homo sapiens This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010],

  • Protein Name:

    CCR4-NOT transcription complex subunit 2

  • Human Gene Id:

    4848

  • Human Swiss Prot No:

    Q9NZN8

  • Mouse Gene Id:

    72068

  • Mouse Swiss Prot No:

    Q8C5L3

  • Specificity:

    Phospho-CNOT2 (S101) Polyclonal Antibody detects endogenous levels of CNOT2 protein only when phosphorylated at S101.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CNOT2; CDC36; NOT2; HSPC131; MSTP046; CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2

  • MolecularWeight(Da):

    59738

  • Function:

    function:The CCR4-NOT complex functions as general transcription regulation complex.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CNOT2/3/5 family.,subunit:Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8.,tissue specificity:Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes.,

  • Subcellular Location:

    cytoplasmic mRNA processing body,nucleus,cytoplasm,cytosol,membrane,CCR4-NOT complex,CCR4-NOT core complex,

  • Expression:

    Fetal kidney,Heart,Kidney,Lymph,Skin,Testis,Thyroid,Umbilical cord

  • Immunohistochemistry analysis of paraffin-embedded human brain, using CNOT2 (Phospho-Ser101) Antibody. The picture on the right is blocked with the phospho peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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CNOT2 (phospho Ser101) Polyclonal Antibody | EnoGene Biotech Co. Ltd