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cGKII (phospho Ser126) Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-61056

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human PKG2. AA range:92-141

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    PRKG2

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

  • Background:

    protein kinase, cGMP-dependent, type II(PRKG2) Homo sapiens This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

  • Protein Name:

    cGMP-dependent protein kinase 2

  • Human Gene Id:

    5593

  • Human Swiss Prot No:

    13237

  • Specificity:

    Phospho-cGKII (S126) Polyclonal Antibody detects endogenous levels of cGKII protein only when phosphorylated at S126.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    PRKG2; PRKGR2; cGMP-dependent protein kinase 2; cGK 2; cGK2; cGMP-dependent protein kinase II; cGKII

  • MolecularWeight(Da):

    87432

  • Function:

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Binding of cGMP results in enzyme activation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 cyclic nucleotide-binding domains.,tissue specificity:Highly concentrated in brain, lung and intestinal mucosa.,

  • Subcellular Location:

    cytosol,apical plasma membrane,nuclear membrane,

  • Expression:

    Pituitary,

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Catalog Number

  • Amount:100ul
  • Price:225$

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cGKII (phospho Ser126) Polyclonal Antibody | EnoGene Biotech Co. Ltd