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Casein Kinase Iγ1/2/3 (phospho Tyr263) Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-61040

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263. AA range:229-278

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    CSNK1G1/CSNK1G2/CSNK1G3

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

  • Immunohistochemistry analysis of paraffin-embedded human brain, using CK-1 gamma1/2/3 (Phospho-Tyr263) Antibody. The picture on the right is blocked with the phospho peptide.

  • Background:

    casein kinase 1 gamma 1(CSNK1G1) Homo sapiens This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],

  • Protein Name:

    Casein kinase I isoform gamma-1/2/3

  • Human Gene Id:

    53944/1455/1456

  • Human Swiss Prot No:

    Q9HCP0/P78368/Q9Y6M4

  • Mouse Gene Id:

    214897/103236/70425

  • Rat Gene Id:

    64086/65278/64823

  • Rat Swiss Prot No:

    Q62761/Q62762/Q62763

  • Specificity:

    Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CSNK1G1; Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G3; Casein kinase I isoform gamma-3; CKI-gamma 3

  • MolecularWeight(Da):

    48511/47457/51389

  • Function:

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,

  • Subcellular Location:

    nucleus,cytoplasm,integral component of membrane,

  • Expression:

    Brain,Muscle,Pooled,

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Catalog Number

  • Amount:100ul
  • Price:225$

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Casein Kinase Iγ1/2/3 (phospho Tyr263) Polyclonal Antibody | EnoGene Biotech Co. Ltd