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IPP-2 (phospho Ser120/S121) Polyclonal Antibody
Datasheet
Catalog Number:
E20-61011Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PPP1R2 around the phosphorylation site of Ser120 and Ser121. AA range:86-135Source:
Polyclonal, RabbitGene Name:
PPP1R2Dilution:
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
- Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PPP1R2 (Phospho-Ser120+Ser121) Antibody
Background:
protein phosphatase 1 regulatory inhibitor subunit 2(PPP1R2) Homo sapiens Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],Protein Name:
Protein phosphatase inhibitor 2Human Gene Id:
5504Human Swiss Prot No:
P41236Mouse Gene Id:
66849Mouse Swiss Prot No:
Q9DCL8Rat Gene Id:
192361Rat Swiss Prot No:
P50411Specificity:
Phospho-IPP-2 (S120/S121) Polyclonal Antibody detects endogenous levels of IPP-2 protein only when phosphorylated at S120/S121.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PPP1R2; IPP2; Protein phosphatase inhibitor 2; IPP-2MolecularWeight(Da):
23015Function:
function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1.,Subcellular Location:
protein phosphatase type 1 complex,Expression:
Epithelium,Heart,Platelet,Skin,Testis,
- Immunohistochemistry analysis of paraffin-embedded human heart, using PPP1R2 (Phospho-Ser120+Ser121) Antibody. The picture on the right is blocked with the phospho peptide.
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Catalog Number
- Amount:100ul
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