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Cell Signal Transduction Research Antibodies

KIR5.1 (phospho Ser416) Polyclonal Antibody

E20-60938Cite ID: EN0049864DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight47936Da
Protein NameInward rectifier potassium channel 16
Mouse Gene Id16517
Rat Swiss Prot NoP52191
SpecificityPhospho-KIR5.1 (S416) Polyclonal Antibody detects endogenous levels of KIR5.1 protein only when phosphorylated at S416.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameKCNJ16; Inward rectifier potassium channel 16; Inward rectifier K(+) channel Kir5.1; Potassium channel; inwardly rectifying subfamily J member 16
Observed Band(KD)48
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from mouse Kir5.1 around the phosphorylation site of Ser417. AA range:369-418
Gene NameKCNJ16
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
BackgroundKCNJ16 (Potassium Voltage-Gated Channel Subfamily J Member 16) is a Protein Coding gene. Diseases associated with KCNJ16 include sesame syndrome and body dysmorphic disorder. Among its related pathways are Transmission across Chemical Synapses and Inwardly rectifying K+ channels. GO annotations related to this gene include inward rectifier potassium channel activity. An important paralog of this gene is KCNJ3. nward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (PubMed: 24561201). he inward-rectifier potassium channel family (also known as 2-TM channels) include the strong inward-rectifier channels (Kir2. ), the G-protein-activated inward-rectifier channels (Kir3. ) and the ATP-sensitive channels (Kir6. ), which combine with sulphonylurea receptors.

Conjugated Antibody

This product is also available conjugated. Format: E20-60938-Conjugate. Price: $485 / Size: 100μl.

E20-60938-FITC$485 / 100μlE20-60938-Biotin$485 / 100μlE20-60938-HRP$485 / 100μlE20-60938-AP$485 / 100μlE20-60938-AF350$485 / 100μlE20-60938-AF405M$485 / 100μlE20-60938-AF488$485 / 100μlE20-60938-AF514$485 / 100μlE20-60938-AF532$485 / 100μlE20-60938-AF555$485 / 100μlE20-60938-AF568$485 / 100μlE20-60938-AF405S$485 / 100μlE20-60938-AF405L$485 / 100μlE20-60938-AF546$485 / 100μlE20-60938-AF594$485 / 100μlE20-60938-AF610$485 / 100μlE20-60938-AF635$485 / 100μlE20-60938-AF647$485 / 100μlE20-60938-AF680$485 / 100μlE20-60938-AF700$485 / 100μlE20-60938-AF750$485 / 100μlE20-60938-AF790$485 / 100μlE20-60938-APC$485 / 100μlE20-60938-PE$485 / 100μlE20-60938-Cy3$485 / 100μlE20-60938-Cy5$485 / 100μlE20-60938-Cy5.5$485 / 100μlE20-60938-Cy7$485 / 100μlE20-60938-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.