FADD (phospho Ser191) Polyclonal Antibody

Name: FADD (phospho Ser191) Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-60838
Price: 225 USD
Availability: InStock

E20-60838Cite ID: EN0049764Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight23279Da

Protein NameProtein FADD

Mouse Gene Id14082

SpecificityPhospho-FADD (S191) Polyclonal Antibody detects endogenous levels of FADD protein only when phosphorylated at S191.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameFADD; MORT1; GIG3; Protein FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity

Observed Band(KD)25

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from mouse FADD around the phosphorylation site of Ser191. AA range:157-206

Gene NameFADD

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

BackgroundThe Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-60838-Conjugate. Price: $485 / Size: 100μl.

E20-60838-FITC$485 / 100μlE20-60838-Biotin$485 / 100μlE20-60838-HRP$485 / 100μlE20-60838-AP$485 / 100μlE20-60838-AF350$485 / 100μlE20-60838-AF405M$485 / 100μlE20-60838-AF488$485 / 100μlE20-60838-AF514$485 / 100μlE20-60838-AF532$485 / 100μlE20-60838-AF555$485 / 100μlE20-60838-AF568$485 / 100μlE20-60838-AF405S$485 / 100μlE20-60838-AF405L$485 / 100μlE20-60838-AF546$485 / 100μlE20-60838-AF594$485 / 100μlE20-60838-AF610$485 / 100μlE20-60838-AF635$485 / 100μlE20-60838-AF647$485 / 100μlE20-60838-AF680$485 / 100μlE20-60838-AF700$485 / 100μlE20-60838-AF750$485 / 100μlE20-60838-AF790$485 / 100μlE20-60838-APC$485 / 100μlE20-60838-PE$485 / 100μlE20-60838-Cy3$485 / 100μlE20-60838-Cy5$485 / 100μlE20-60838-Cy5.5$485 / 100μlE20-60838-Cy7$485 / 100μlE20-60838-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.