Product Information
Molecular Weight38155Da
Protein NameProtein Tob1
Human Gene Id10140
Human Swiss Prot NoP50616
Mouse Swiss Prot NoQ61471
Rat Swiss Prot NoQ8R5K6
SpecificityPhospho-TOB1 (S164) Polyclonal Antibody detects endogenous levels of TOB1 protein only when phosphorylated at S164.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTOB1; TOB; TROB1; Protein Tob1; Transducer of erbB-2 1
Observed Band(KD)40
Functionfunction:Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.,PTM:Phosphorylated on Ser and Thr residues.,similarity:Belongs to the BTG family.,subunit:Interacts with CNOT7.,tissue specificity:Ubiquitous.,
Subcellular LocationCytoplasm . Nucleus . Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic. .
ExpressionUbiquitous.
BackgroundThis gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],