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IPP-2 (phospho Ser44) Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-60830

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    Synthesized phospho-peptide around the phosphorylation site of human IPP-2 (phospho Ser44)

  • Source:

    Polyclonal, Rabbit

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

  • Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night

  • Background:

    protein phosphatase 1 regulatory inhibitor subunit 2(PPP1R2) Homo sapiens Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

  • Protein Name:

    Protein phosphatase inhibitor 2

  • Human Gene Id:

    5504

  • Human Swiss Prot No:

    P41236

  • Mouse Gene Id:

    66849

  • Mouse Swiss Prot No:

    Q9DCL8

  • Rat Gene Id:

    192361

  • Rat Swiss Prot No:

    P50411

  • Specificity:

    Phospho-IPP-2 (S44) Polyclonal Antibody detects endogenous levels of IPP-2 protein only when phosphorylated at S44.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    PPP1R2; IPP2; Protein phosphatase inhibitor 2; IPP-2

  • MolecularWeight(Da):

    23015

  • Observed Band(KD):

    44

  • Function:

    function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1.,

  • Subcellular Location:

    protein phosphatase type 1 complex,Subcellular Location:protein phosphatase type 1 complex,

  • Expression:

    Epithelium,Heart,Platelet,Skin,Testis,

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Catalog Number

  • Amount:100ul
  • Price:225$

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