NUDC (phospho Ser326) Polyclonal Antibody

Name: NUDC (phospho Ser326) Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-60826
Price: 225 USD
Availability: InStock

E20-60826Cite ID: EN0049752Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight38243Da

Protein NameNuclear migration protein nudC

Human Gene Id10726

Human Swiss Prot NoQ9Y266

Mouse Gene Id18221

Mouse Swiss Prot NoO35685

Rat Gene Id29648

Rat Swiss Prot NoQ63525

SpecificityPhospho-NUDC (S326) Polyclonal Antibody detects endogenous levels of NUDC protein only when phosphorylated at S326.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameNUDC; Nuclear migration protein nudC; Nuclear distribution protein C homolog

Observed Band(KD)45

Functionfunction:Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.,induction:Up-regulated in actively dividing hematopoietic precursor cells. Up-regulated in cultured erythroleukemia TF-1 cells by granulocyte-macrophage colony-stimulating factor. Strongly down-regulated during maturation of erythroid precursor cells.,PTM:Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.,similarity:Belongs to the nudC family.,similarity:Contains 1 CS domain.,subcellular location:In a filamentous pattern adjacent to the nucleus of migrating cerebel

Subcellular Locationnucleoplasm,cytoplasm,cytosol,microtubule,cell-cell adherens junction,integral component of membrane,

ExpressionEpithelium,Eye,Heart,Kidney,Lung,Periodontal ligament,Pitui

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human NudC around the phosphorylation site of Ser326. AA range:282-331

Gene NameNUDC

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Backgroundnuclear distribution C, dynein complex regulator(NUDC) Homo sapiens This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-60826-Conjugate. Price: $485 / Size: 100μl.

E20-60826-FITC$485 / 100μlE20-60826-Biotin$485 / 100μlE20-60826-HRP$485 / 100μlE20-60826-AP$485 / 100μlE20-60826-AF350$485 / 100μlE20-60826-AF405M$485 / 100μlE20-60826-AF488$485 / 100μlE20-60826-AF514$485 / 100μlE20-60826-AF532$485 / 100μlE20-60826-AF555$485 / 100μlE20-60826-AF568$485 / 100μlE20-60826-AF405S$485 / 100μlE20-60826-AF405L$485 / 100μlE20-60826-AF546$485 / 100μlE20-60826-AF594$485 / 100μlE20-60826-AF610$485 / 100μlE20-60826-AF635$485 / 100μlE20-60826-AF647$485 / 100μlE20-60826-AF680$485 / 100μlE20-60826-AF700$485 / 100μlE20-60826-AF750$485 / 100μlE20-60826-AF790$485 / 100μlE20-60826-APC$485 / 100μlE20-60826-PE$485 / 100μlE20-60826-Cy3$485 / 100μlE20-60826-Cy5$485 / 100μlE20-60826-Cy5.5$485 / 100μlE20-60826-Cy7$485 / 100μlE20-60826-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.