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Cell Signal Transduction Research Antibodies
Cdc37 (phospho Ser13) Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight44468Da
Protein NameHsp90 co-chaperone Cdc37
Human Gene Id11140
Human Swiss Prot NoQ16543
Mouse Gene Id12539
Mouse Swiss Prot NoQ61081
Rat Gene Id114562
Rat Swiss Prot NoQ63692
SpecificityPhospho-Cdc37 (S13) Polyclonal Antibody detects endogenous levels of Cdc37 protein only when phosphorylated at S13.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDC37; CDC37A; Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37
Observed Band(KD)44
Functionfunction:Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.,PTM:Constitutively sumoylated by UBE2I.,similarity:Belongs to the CDC37 family.,subunit:Forms a complex with Hsp90. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.,
Subcellular Locationcytoplasm,cytosol,extracellular exosome,HSP90-CDC37 chaperone complex,
ExpressionLymph,Placenta,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDC37 around the phosphorylation site of Ser13. AA range:1-50
Gene NameCDC37
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundcell division cycle 37(CDC37) Homo sapiens The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-60751-Conjugate. Price: $485 / Size: 100μl.
E20-60751-FITC$485 / 100μlE20-60751-Biotin$485 / 100μlE20-60751-HRP$485 / 100μlE20-60751-AP$485 / 100μlE20-60751-AF350$485 / 100μlE20-60751-AF405M$485 / 100μlE20-60751-AF488$485 / 100μlE20-60751-AF514$485 / 100μlE20-60751-AF532$485 / 100μlE20-60751-AF555$485 / 100μlE20-60751-AF568$485 / 100μlE20-60751-AF405S$485 / 100μlE20-60751-AF405L$485 / 100μlE20-60751-AF546$485 / 100μlE20-60751-AF594$485 / 100μlE20-60751-AF610$485 / 100μlE20-60751-AF635$485 / 100μlE20-60751-AF647$485 / 100μlE20-60751-AF680$485 / 100μlE20-60751-AF700$485 / 100μlE20-60751-AF750$485 / 100μlE20-60751-AF790$485 / 100μlE20-60751-APC$485 / 100μlE20-60751-PE$485 / 100μlE20-60751-Cy3$485 / 100μlE20-60751-Cy5$485 / 100μlE20-60751-Cy5.5$485 / 100μlE20-60751-Cy7$485 / 100μlE20-60751-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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